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Promacot (Promethazine)
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Promacot

Promacot has mutliple uses. It is most often used to prevent or treat nausea and vomiting related to certain conditions. It is also used to treat allergic reactions or allergy symptoms. Lastly, it can also be used as a sedative before and after surgery and medical procedures.

Other names for this medication:
Admol, Avomine, Basiprom, Biodol, Calmkid, Ceedokid, Cofcodyl, Emispan, Enimol, Ethamol, Fevril, Hyperex, Kelvin, Lagesic, Lincotuss, Metacet, Nimkair, Paracee, Paramax, Parapro, Phenomet, Pizol, Primozyn, Procalm, Propar, Prophen, Prosip, Prosym, Prozine, Pyrhist, Synergan, Tixylix, Tussdex, Tymol, Vomica, Vomin

Similar Products:
Clarinex, Lopid, Zantac, Mysoline, Feldene, Addyi, Abilify, Nizoral, Elocon, Remeron, Zioprin, Symkast, Lamogin, Varbend, Klabax, Simperten, Locric,

Also known as: Promethazine

Description

Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.

Cough/cold combination products contain more than one ingredient. For example, some products may contain an antihistamine, a decongestant, and an analgesic, in addition to a medicine for coughing. If you are treating yourself, it is important to select a product that is best for your symptoms. Also, in general, it is best to buy a product that includes only those medicines you really need. If you have questions about which product to buy, check with your pharmacist.

Since different products contain ingredients that will have different precautions and side effects, it is important that you know the ingredients of the medicine you are taking. The different kinds of ingredients that may be found in cough/cold combinations include:

Antihistamines—Antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They also help relieve some symptoms of the common cold, such as sneezing and runny nose. They work by preventing the effects of a substance called histamine, which is produced by the body. Some examples of antihistamines contained in these combinations are:

Bromodiphenhydramine Brompheniramine Carbinoxamine Chlorpheniramine Dexchlorpheniramine Diphenhydramine Doxylamine Phenindamine Pheniramine Phenyltoloxamine Pyrilamine Promethazine Triprolidine

Decongestants—Decongestants produce a narrowing of blood vessels. This leads to clearing of nasal congestion. However, this effect may also increase blood pressure in patients who have high blood pressure. These include:

Ephedrine Phenylephrine Pseudoephedrine

Antitussives—Antitussives help relieve coughing and are some contain a narcotic. These antitussives act directly on the cough center in the brain. Narcotics may become habit-forming, causing mental or physical dependence, if used for a long time. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.

Narcotic antitussives Codeine Dihydrocodeine Hydrocodone Hydromorphone

Non-narcotic antitussives Carbetapentane Caramiphen Dextromethorphan

Expectorants—Expectorants work by loosening the mucus or phlegm in the lungs. The main expectorant used in cough and cold medicines is guaifenesin. Other ingredients added as expectorants (for example, ammonium chloride, calcium iodide, iodinated glycerol, ipecac, potassium guaiacolsulfonate, potassium iodide, and sodium citrate) have not been proven to be effective. In general, the best thing you can do to loosen mucus or phlegm is to drink plenty of water.

Analgesics—Analgesics are used in these combination medicines to help relieve the aches and pain that may occur with the common cold. These include:

Acetaminophen Aspirin Other salicylates such as salicylamide and sodium salicylate

The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large amounts of both medicines are taken together for a long time. However, taking the recommended amounts of combination medicines that contain both acetaminophen and a salicylate for short periods of time has not been shown to cause these unwanted effects.

Anticholinergics—Anticholinergics, such as homatropine may help produce a drying effect in the nose and chest.

These cough and cold combinations are available both over-the-counter (OTC) and with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

Dosage

Take Promacot exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Promacot is often taken at bedtime or before meals. For motion sickness, Promacot is usually started within 1 hour before traveling. When used for surgery, Promacot is usually taken the night before the surgery.

How often you take Promacot and the timing of your dose will depend on the condition being treated.

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

If a child is using this medicine, tell your doctor if the child has any changes in weight. Promacot doses are based on weight in children, and any changes may affect your child's dose.

Call your doctor if your symptoms do not improve, or if they get worse while using Promacot.

This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using Promacot.

Store Promacot at room temperature away from moisture, heat, and light.

Detailed Promacot dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Keep the liquid form of this medicine from freezing. Do not refrigerate the syrup.

Detailed Codeine/promethazine dosage information

Side effects

The most common side effects associated with Promacot are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Insufficient information is available on the relationship of age to the effects of promethazine in geriatric patients. However, elderly patients may be more sensitive to the side effects of this medicine (such as confusion and severe drowsiness) than in younger adults, and are more likely to have age-related heart or blood vessel disease, liver problems, and kidney disease, which may require adjustment of dosage in patients receiving promethazine .

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Regions of potential biological importance are identified using various sequence motifs, and then the results are displayed as their cumulative statistically weighted distribution. The literature suggests that a sustainable system has clearly-defined goals around which stakeholders can rally, but this has not been achieved in the systems studied. The PCP-induced behaviours in animals that had exhibited tolerance and sensitization to PCP (10 mg kg-1 day-1) were not influenced by acute L-NAME (5 and 50 mg kg-1, i.p.) or D-NAME (50 mg kg-1, i.p.) treatment. Fibroblasts were grown on collagen I-coated glass or hydrogel substrates of discrete stiffnesses, spanning the range of normal and fibrotic lung tissue. A 53-year-old white woman presented with a 5-month history of throat pain. A survey of the outbreak of dengue fever and evaluation of preventive effect.

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By analysis of top 20 upregulated genes in mouse tracheal epithelial cells (MTEC) of Gprc5a knockout (KO) vs wild-type (WT), we found that ceruloplasmin, lipocalin-2, and periostin are not only upregulated in lung epithelial cells of Gprc5a-ko mice, but also expressed at high levels in lung tumor tissues of Gprc5a-ko mice. Rho pathway inhibition blocked VEGF-induced fibronectin upregulation. The nigroxins are antigenically similar and constitute a new antigenic subclass of PLA(2)s. Future developments in this area could benefit from systems thinking and insights from theoretical perspectives, such as sociotechnical system theory for joint optimization and responsible autonomy, with emphasis on both the technical and social aspects of HRA implementation. crispatus slpA promotes ESC growth mainly through an ERK1/2-dependent pathway. A retrospective chart review of the last 200 consecutive hysterectomy cases completed before and after implementation of a robotics program (Canadian Task Force classification III). Hemopoietic activities of cryopreserved murine fresh and postmortem bone marrow cells. This process generally excludes the possibility that the two strands of a given stretch of DNA can each harbor a gene in an overlapping manner. A G protein-and tyrosine kinase-dependent but protein kinase C-independent activation of mitogen-activated protein kinases is involved in the regulation of taurocholate excretion by liver cell hydration changes.

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Erythematous patches with keratotic annular borders on the glans penis. The immunological relationships between the Mr 16,000 and Mr 12,000 factors and TGF beta were therefore studied using neutralizing anti-TGF beta antibodies. Behavioural thermoregulation by subyearling fall (autumn) Chinook salmon Oncorhynchus tshawytscha in a reservoir. The HIV-1 envelope protein gp120 induces neuronal apoptosis in hippocampal slices. Magnetic resonance imaging findings of orbital disease in neurofibromatosis type 1 patients. Most organelles followed a general pattern whereby preexisting proteins are symmetrically partitioned followed by template-based incorporation of new proteins. These observations are discussed in the light of site-directed studies on the R. The AtGenExpress hormone and chemical treatment data set: experimental design, data evaluation, model data analysis and data access.

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Although there are some case reports of successful treatment with oral epidermal growth factor receptor tyrosine kinase inhibitors or pemetrexed, an effective therapeutic strategy for this type of lung cancer has not been established. Transsphenoidal surgical treatment generally yields normalization or improvement of visual field defects. Antioxygenic enzyme activities in differentiating human neuroblastoma cells. As skin inflammation may serve as a model for chronic inflammatory disorders, it is likely that miRNAs involved in skin inflammation will eventually emerge in other inflammatory or autoimmune disorders, and some of these may become disease markers and therapeutic targets. The level of expression of the downstream gene was 0.30 to 0.36 that of the upstream one. Linear regression analysis showed a significant negative relationship between cell area and PGE2 synthesis.

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Inter and intra-estuary variability in ingress, condition and settlement of the American eel Anguilla rostrata: implications for estimating and understanding recruitment. Fast reversibility of glucose-induced desensitization in rat pancreatic islets. Treatment of a knee contracture using a knee orthosis incorporating stress-relaxation techniques. Among a total of 83 inhibitors, eight were identified as inhibitors with antiviral activity. Additional biological marker for predicting tumor recurrence could potentially be used in the decision making process and could alter the frequency of clinical cystoscopy.

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Atrioventricular asynchrony was associated with higher mean (SD) concentrations of atrial natriuretic peptide (231.9 (123.1) v 53.5 (38.8) pg/ml) and an increased mean (SD) calf capillary filtration coefficient (4.2 (1.1) v 3.6 (1.1) ml/min.mm Hg.100 ml x 10(-3)), but there was no correlation between the magnitude of the change in these variables in individual patients. Swi5 is involved in the transcriptional activation of the HO gene during late G1 and early S phase, and Ace2 induces CTS1 transcription during early and late G1 We show that Swi5 activates EGT2 transcription as soon as it enters the nucleus at the end of mitosis in a concentration-dependent manner. Quantitative radioautographic light and electron microscopic analysis of the localization of monoamines in the median eminence of the rat. The autostereoscopic Setred system was regarded as helpful in establishing the surgical strategy and analyzing the pathoanatomical situation compared with conventional planning. Early and mild acute rejection episodes do not usually cause chronic renal allograft rejection. The authors reported a retrograde cavernous sinus thrombosis and orbital cellulitis in an immunocompetence child, due to meningitis. This study sought to compare, head to head, the two most popular pharmacologic stress echocardiographic tests--dipyridamole and dobutamine--with state of the art protocols in a large multicenter prospective study.

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On the Breaking up of Fat in the Alimentary Canal under Normal Circumstances and in the Absence of the Pancreas. The patient had no clinical, biochemical or visual signs of disease recurrence 6 months postoperatively. During CNS development, even-skipped expression starts in the ganglion mother cell resulting from the first asymmetric division of neuroblast NB 1-1. Differential homogenization and amplification of two satellite DNAs in the genus Cucurbita (Cucurbitaceae). In endplate regions of the diaphragm, prednisone treatment had no effect on the density of toxin binding sites, either when given alone or when administered in conjunction with neostigmine while neostigmine was observed to reduce specific binding to less than half after one week. Thrombectomy during PCI for acute myocardial infarction: are the randomized controlled trial data relevant to the patients who really need this technique?. Endoscopic polypectomy has, therefore, become an accepted screening and surveillance modality for CRC and has been widely adopted by clinicians, policymakers, and professional organizations as an effective screening tool. The tumor burden of locally recurrent breast cancer is a neglected prognostic factor. Minocycline mitigates isoflurane-induced cognitive impairment in aged rats.

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Differing time courses between delta lactate and mitochondrial respiration during coronary occlusion and after reperfusion in canine hearts. Immunological characterization of lymphocytes in lymphoproliferative diseases. Mutations affecting the cytoplasmic domain of the Moloney murine leukemia virus envelope protein: rapid reversion during replication. However, only the M2 protein could cause an increase in the level of LC3-II, which is an indicator of autophagic activity. This article addresses the issue of whether the remember-know (RK) task is best explained by a single-process or a dual-process model. No statistically significant difference was found between the groups. To confirm the inducing role of BEX3 on OCT4 expression, we knockdown BEX3 using siRNA and compared the expression of OCT4 with mock transfectants. Exclusion of linkage to the entire region in one family proves genetic heterogeneity. Intracardiac fibrin adhesive for selective fetocide in twin pregnancy: report of three cases.

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Additive log-logistic model for networked video quality assessment. Annotated and unreviewed Lepidopteran chorion protein sequences are temovate generic available in various databases. Here, we show that IT injection of IC resulted in enhanced antitumor effects against B16-KSA melanoma, NXS2 neuroblastoma, and human M21 melanoma xenografts when compared to intravenous (IV) IC injection. The treatment of myelinating dorsal root ganglion (DRG) explant cultures from neuropathic mice with RM (25 nm) improved the processing of PMP22 and increased the abundance and length of myelin internodes, as well as the expression of myelin proteins. Magnetization transfer in hemopoietic bone marrow examined by localized proton spectroscopy. TNF-alpha was not detectable in the supernatants of stromal cell cultures prepared from endometrial tissue obtained at any time in the menstrual cycle. Biliary distensibility during per-operative cholangiography as compared to pre-operative ultrasound: a four year follow-up study. Mycoplasma hyponeumoniae and Mycoplasma hyosynoviae infection in cases of fibrinous pericarditis in slaughter pigs. Diazepam (DZ) at doses of 0.5, 1.0, 2.0, 4.0, or 6.0 mg/kg resulted in a significant (p less than 0.05) increase in the mean response times (MRT) during the 2 hr test session in terms of percent change from baseline performance under nondrug conditions measured the day prior to drug treatment.

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Forty stroke patients (aged from 42 to 65 years) with ankle plantarflexor spasticity. Sequelae of pediatric hip disorders: survey responses from experts in adult hip reconstruction. Fewer females exposed to rat urine of either sex produced litters. Self-titration of the opiate dosage on demand can decrease the incidence of serious side effects. Results of this study show that in 2014 more than half of AMI patients arrive at emergency medical centers after the golden time for proper treatment of AMI. A constructed expression plasmid, pEXPMTII, in which human metallothionein-IIA cDNA was inserted downstream of a tryptophan-lactose promoter, was used to transform Escherichia coli JM105 strain.

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Congenital methemoglobinemia due to NADH can you take allergy medicine and flonase together -methemoglobin reductase deficiency: report of a case. The degree of germinal epithelial loss per 100 tubules was calculated by assigning a value to each grade according to the severity of loss of germinal epithelium. Evaluation of the effect of oxidative stress and vitamin E supplementation on renal function in rats with streptozotocin-induced Type 1 diabetes. The sequence analysis indicated that nsp4 genes share multi-phyletic origin of evolution and exhibit species independent genetic diversity. We derive these waves by considering imaginary displacements on spherical fields, leading to simple closed-form expressions.

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BMI, age, triglyceride, CRP and fatty liver were independent variables predicting VAT volume. A resetting procedure has been incorporated that successfully discourages any misuse of the system. Urolithiasis in children--rational diagnosis, therapy, and metaphylaxis. In very low birth weight infants abdominal emergency surgery may result in ileostomy formation. Of three oocytes retrieved, two fertilized and were cryopreserved. Herpes simplex virus type 1 encodes a helicase-primase complex mometasone nasal spray drug class composed of the products of the UL5, UL52, and UL8 genes. The practical use of these diverse stable isotopically labeled biochemicals provide safe, ethical, noninvasive investigation of nutritional metabolism in humans. Remarks on Depletion and Excessive (?) Stimulation in Very Serious Cases of Acute Disease.

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Patients taking certain psychotropic medications should be advised not to drive. Sociodemographic analysis of drug use among adolescent athletes: observations-perceptions of athletic directors-coaches. It is characterised by atypical clinical features which makes the diagnosis difficult. In summary, our results suggest that the absence of PsbO in Synechocystis affects the coordination of photosynthesis/respiration and l-arginine metabolism through complex probably redox-mediated regulatory pathways. To determine the intra- and inter-reader reliability of MRI parameters relevant to patients with intervertebral disc herniation (IDH), including disc morphology classification, degree of thecal sac compromise, grading of nerve root impingement, and measurements of cross-sectional area of the spinal canal, thecal sac, and disc fragment. Post-operative sore throat: effect of lignocaine jelly and spray with endotracheal intubation. The safety of osmotically acting cathartics in colonic cleansing. History of depression and risk of hyperemesis gravidarum: a population-based cohort study.

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Lengths of stay in residential treatment were significantly longer than in day hospital, but costs per week were lower. Polyglutamine expansion in huntingtin (Htt) and the androgen receptor (AR) causes untreatable neurodegenerative diseases. Such neural architecture, able to autonomously learn complex associations is envisaged to be a suitable basis for an immediate implementation within an robot control architecture. Acute appendicitis (AA) is the most common cause of acute abdomen during pregnancy. There are few reports on the burden of disease of MS, worldwide. Ethics in health care and research is based on the fundamental principle of informed consent. We have demonstrated that inhibitors such as the naturally occurring flavonoids having 5,7-dihydroxy substituents can bind to human placental cytochrome P-450 with affinity comparable to their ability to inhibit aromatization of androstenedione and testosterone to oestradiol and oestrone, respectively.

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