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Emispan (Promethazine)

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Emispan works by blocking the action of histamine, thereby relieving these symptoms. It also works directly on several areas of the brain to prevent nausea/vomiting and help you feel more relaxed.

Other names for this medication:
Aceegan, Admol, Avomine, Basiprom, Brumol, Calmkid, Citazine, Cofcodyl, Crophen, Emispan, Enimol, Ethamol, Fevril, Hyperex, Ibuprom, Kidkof, Lagesic, Metacet, Nimkair, Paramax, Parapro, Petrox, Phenomet, Pinex, Primozyn, Promacot, Promegan, Promethegan, Propar, Prophen, Prosed, Prosip, Prosym, Prozine, Pyrex, Pyrhist, Pyrivin, Romet, Symol, Tixylix, Tymol, Vomin

Similar Products:
Maxalt, Cardura, Desyrel, Sustiva, Thorazine, Sinequan, Intagra, Albenza, Lamivudine, Anxofit, Hipres, Liporest, Etilive, Pinex,

Also known as: Promethazine


Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.

Cough/cold combination products contain more than one ingredient. For example, some products may contain an antihistamine, a decongestant, and an analgesic, in addition to a medicine for coughing. If you are treating yourself, it is important to select a product that is best for your symptoms. Also, in general, it is best to buy a product that includes only those medicines you really need. If you have questions about which product to buy, check with your pharmacist.

Since different products contain ingredients that will have different precautions and side effects, it is important that you know the ingredients of the medicine you are taking. The different kinds of ingredients that may be found in cough/cold combinations include:

Antihistamines—Antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They also help relieve some symptoms of the common cold, such as sneezing and runny nose. They work by preventing the effects of a substance called histamine, which is produced by the body. Some examples of antihistamines contained in these combinations are:

Bromodiphenhydramine Brompheniramine Carbinoxamine Chlorpheniramine Dexchlorpheniramine Diphenhydramine Doxylamine Phenindamine Pheniramine Phenyltoloxamine Pyrilamine Promethazine Triprolidine

Decongestants—Decongestants produce a narrowing of blood vessels. This leads to clearing of nasal congestion. However, this effect may also increase blood pressure in patients who have high blood pressure. These include:

Ephedrine Phenylephrine Pseudoephedrine

Antitussives—Antitussives help relieve coughing and are some contain a narcotic. These antitussives act directly on the cough center in the brain. Narcotics may become habit-forming, causing mental or physical dependence, if used for a long time. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.

Narcotic antitussives Codeine Dihydrocodeine Hydrocodone Hydromorphone

Non-narcotic antitussives Carbetapentane Caramiphen Dextromethorphan

Expectorants—Expectorants work by loosening the mucus or phlegm in the lungs. The main expectorant used in cough and cold medicines is guaifenesin. Other ingredients added as expectorants (for example, ammonium chloride, calcium iodide, iodinated glycerol, ipecac, potassium guaiacolsulfonate, potassium iodide, and sodium citrate) have not been proven to be effective. In general, the best thing you can do to loosen mucus or phlegm is to drink plenty of water.

Analgesics—Analgesics are used in these combination medicines to help relieve the aches and pain that may occur with the common cold. These include:

Acetaminophen Aspirin Other salicylates such as salicylamide and sodium salicylate

The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large amounts of both medicines are taken together for a long time. However, taking the recommended amounts of combination medicines that contain both acetaminophen and a salicylate for short periods of time has not been shown to cause these unwanted effects.

Anticholinergics—Anticholinergics, such as homatropine may help produce a drying effect in the nose and chest.

These cough and cold combinations are available both over-the-counter (OTC) and with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .


This section provides information on the proper use of a number of products that contain promethazine. It may not be specific to Emispan. Please read with care.

A nurse or other trained health professional will give you this medicine. This medicine is given as a shot into a muscle or into a vein.

Your doctor will give you a few doses of this medicine until your condition improves, and then switch you to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Detailed Emispan dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include overactive reflexes, loss of coordination, severe drowsiness or weakness, fainting, dilated pupils, weak or shallow breathing, or seizure (convulsions).


Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Keep the liquid form of this medicine from freezing. Do not refrigerate the syrup.

Detailed Codeine/promethazine dosage information

Side effects

The most common side effects associated with Emispan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Emispan VC may cause blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Drinking alcohol can increase certain side effects of promethazine.

Ask a doctor or pharmacist before using any other cold, cough, allergy, or sleep medicine. Antihistamines and decongestants are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains an antihistamine or decongestant.

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Short-term outcome of endoscopic versus microscopic pituitary adenoma surgery: a systematic review and meta-analysis. The action of piroxicam in the perfused rat liver metabolism seems to be a consequence of its action on mitochondria. Programmed cell death (PCD) or apoptosis has crucial roles in the development of the nervous system and in tissue homeostasis. Unlike 6-hydroxydopamine, 6-mercaptodopamine was resistant to autoxidation at pH 7.4. In order to outline basic concepts for the design of a bacterial aerosol infection model, the development of a pig model with Actinobacillus pleuropneumoniae is described.

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Epitope analysis revealed that the purified antibody reacted only with mu-calpain N-terminal peptides containing N-acetyl SEETT structure but no reactions occurred with other analogous peptides. Such variations are important for the spatial interpretation of vascular responses to flow and for an understanding of mechanotransduction mechanisms at the level of single cells. Increased expression of IRAK1 could be responsible, in part, for sex-specific responses to infection and subsequent immune advantage in female neonates. Subjective PROs and objective range of motion (ROM) were obtained at baseline and through to 60 months. These spectra demonstrate the advantages of the PISEMA experiment over conventional approaches to separated local-field spectroscopy, especially the high resolution in the dipolar dimension where the spinning sidebands have uniformly narrow linewidths. Expression was not evident 30 min after treatment with phorbol ester, was increased within 3-4 h after treatment, reached a maximum after 8 h and then declined to low levels 24 h after treatment. The toxin causing the gastroenteritis and other lesions is unknown. Bed fires in carbon canisters are not uncommon and can present a significant safety hazard at facilities if proper safety measures are not implemented. However, the major impact of his work has been the development of adhesive restorative techniques.

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Vaccinia virus RNA helicase: nucleic acid specificity in duplex unwinding. Unlike its natural product parent, FTY720 does not interfere with sphingolipid biosynthesis. Reports on the Nursing and Administration of Provincial Workhouses and Infirmaries. A chimeric oligonucleotide composed of DNA and modified RNA residues was used to direct correction of the mutation in the hemoglobin betaS allele. Joint Attention and Brain Functional Connectivity in Infants and Toddlers. Various pharmacological pathways are already exploited to involve this heptapeptide in therapy as both inhibitors of angiotensin-converting enzyme and angiotensin II type 1 receptor blockers increase its levels. A 62 year old man presented a diffuse hemorrhagic syndrome related to the presence of an acquired factor VII inhibitor (proconvertin). Family studies and changing concepts of personality development. Novel Polyfluorinated Compounds Identified Using High Resolution Mass Spectrometry Downstream of Manufacturing Facilities near Decatur, Alabama.

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Position, form, dimensions and fine structure of the mesencephalic trigeminal nucleus of the domestic chicken are described. Enterohaemorrhagic Escherichia coli: a new problem, an old group of organisms. This permitted quantitative evaluation of stacking interactions between the m7G cap and the tryptophan indole ring, and the relative orientations of the planes of the two rings, spaced about 3.2 angstroms apart. The mechanisms underlying tumor radioresistance are manifold and, in part, accredited to a special subpopulation of tumorigenic cells. To use amniotic membranes as a buffer between the cornea and radioactive eye plaques. This antigen was expressed in the deep portion of metaplastic glands and cancers in the stomach. The fbpABC locus of Neisseria gonorrhoeae functions in the periplasm-to-cytosol transport of iron. A possible explanation for this may be the fact that neuropathic pain is a highly disabling symptom and, consequently, there is a demand from patients and health professionals for a definitive remedy to treat this pain. Since no complete ORF1 was conserved in pK192 plasmids, these results lead to the conclusion that the ORF1 gene is necessary for the replication and/or maintenance of pGKL1.

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An attempt was made to approximate in vivo conditions by using urine as a test medium and correlating the activity of nal in urine with its activity in nutrient, Trypticase soy, brain-heart infusion, and Mueller-Hinton broths. Sleep disturbance in people with heart failure: implications for self-care. 3-month-old prenatally stressed and control rats were treated for 21 days with imipramine, fluoxetine or tianeptine (10mg/kg/day i.p.).The impact of chronic antidepressant administration was examined in forced swim test. Despite having a wealth of FDA-approved therapeutic options for type 2 diabetes majorities of the patients are not able to achieve the appropriate glycemic control due to various factors. This review discusses progress in the preparation of tyrosinamide-oligosaccharides from different glycoproteins and their utility in glycobiology research. This study focused on the functional role of inositol 1,4,5-trisphosphate receptor type 1 (IP3R1) in rat hippocampus after neonatal anoxia. Update: methods to transmit fire alarm signals--manual transmission permitted under certain circumstances. The previous administration of Zn to stress or endotoxin treatments increased MT levels by 35- and 42-fold, respectively, indicating a synergistic effect in both cases. Oligocyclic and macrocyclic diterpene esters from latices of some Euphorbia species utilized as source plants of honey. The existence of these organisms in lesions and non-digestive organs in such animals and man, however, has been unknown as yet.

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Whether TAMs have a positive or negative effect also depends on the macrophage activation state, the status of tumor development, and the anatomic locus of macrophage infiltration. Our study highlights the role of total cholesterol and blood inflammatory marker levels in enhancing ETP in morbidly obese patients. Short-term ozone exposure causes lung function decrements, increased airway reactivity, airway inflammation, increased respiratory symptoms and hospital admissions. In view of this common etiology in these diseases, targeting the recruitment, activation and regulation of dysfunctional macrophages represents a promising therapeutic strategy. Novel insights into fatty acid oxidation, amino acid metabolism, and insulin secretion from studying patients with loss of function mutations in 3-hydroxyacyl-CoA dehydrogenase. This descriptive study included seventy cancer patients staying in the oncology and internal disease clinics of a university hospital in Turkey. Effect of amino acids and amino acid derivatives on crystallization of hemoglobin and ribonuclease A. One key challenge remains the prediction of the amino acids in a given protein sequence that are involved in protein-protein interactions. To investigate their potential structural and functional roles, we have cloned and expressed Xenopus HMG1 and histone B4.

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Objective The aim of the present study was to determine the effects of hospital-based eHealth technologies on quality, safety and efficiency of care and clinical outcomes.Methods Systematic reviews and reviews of systematic reviews of eHealth technologies published in PubMed/Medline/Cochrane Library between January 2010 and October 2015 were evaluated. The management involves early detection, treatment with appropriate antibiotics and doing surveillance culture to identify the possible source of infection. The current account has not been modified or updated since 1985. Vaginal degeneration following implantation of synthetic mesh with increased stiffness. Changes in the physicochemical properties of autotransfused UV-irradiated blood. However it remains to be determined how OASIS is implicated in gliotic reaction. Somatic mutations within the antibody variable domains are critical to the immense capacity of the immune repertoire.

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Frequently, aneugens are detected using the in vitro micronucleus assay (IVM), with either centromere or kinetochore labeling. Antenatal molecular diagnosis is technically straightforward to perform. Increased energy flux (by means of decreased intake or increased output) may provide a simple and inexpensive approach to reducing the risk of cancer in man. No consistent findings about predictors emerged when such pretreatment variables as demographics and severity of symptoms were used to predict the outcome. The results indicate that iodixanol does not activate the complement cascade when added to human serum, and that it is unlikely that anaphylactoid reactions observed in man after CM theophylline er 300 mg tab ale administration are caused by CM-induced anaphylatoxins. Retinol dehydrogenase 10 is indispensible for spermatogenesis in juvenile males. Arabidopsis is the dominating model species for plant developmental biology, but other species serve as models for processes that cannot be studied in Arabidopsis, such as compound leaf or wood formation, or to test the universality of developmental mechanisms initially identified in Arabidopsis. Because of this important advantage over conventional clips, titanium clips should be considered for routine use in aneurysm surgery. Among them the reticular nucleus is distinguished, it sends its efferent fibers from the ventral, ventrolateral and lateral areas.

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Volumetric image-rendering allows for precise in vivo measurements of anatomic distances in 3-D space. Effectiveness of Integrated Best Management Practices on Mitigation of Atrazine and Metolachlor in an Agricultural Lake Watershed. With the increasing average donor age and the advent of Model for End-stage Liver Diseases (MELD) score-based allocation criteria, an optimal donor/recipient matching is often unsuitable. Peptide-functionalized starPEG/heparin hydrogels direct mitogenicity, cell morphology and cartilage matrix distribution in vitro and in vivo. to examine the effect of cycle phase or a low dose oral contraceptive on exercise performance in young women. Formyl-methionylleucylphenylalanine (fMLP) at 0.25 nM inhibited the PMN adherence but was stimulated at 10 or 100 nM. Most cases of SCLE are idiopathic, but occasional cases may be drug-induced or associated with a hereditary deficiency of complement components.

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Additional doses (0.12-0.24 g/kg i.v.) of urethane dose-dependently reduced the elevations in the discharge rate of reticulospinal vasomotor and sympathetic colcrys dosage forms neurons and of arterial pressure, elicited by stimulating the carotid chemoreceptors with intra-carotid injections of sodium cyanide (100 nmol/10 microl), without affecting discharges of the carotid chemoafferents. A cross-sectional study of musculoskeletal symptoms and risk factors in semiconductor workers. MRI techniques for prediction of local tumor progression after high-intensity focused ultrasonic ablation of prostate cancer. Androgen-independent cancer cells exhibit more EGFR expression and phosphorylation than do androgen-responsive prostate cancer cells. Proteomic profiling in liver samples using classification and regression tree algorithms is a promising technique to differentiate healthy subjects from CRLM patients and to classify the severity of CRLM patients.

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Fertility treatment includes hormonal stimulation of the woman and in vitro manipulation of gametes and embryos that may influence prenatal brain development. Decrease of acid phosphatase activity in the epithelial cells from inflamed gingivae. Lead selection: old and new methods for locating the most electrocardiogram information. Comparing the predictive utility of two screening tools for mental disorder among probationers. These findings may suggest a role of a platelet aggregation defect in haemorrhagic diathesis complicating systemic amyloidosis. A systemic survey demonstrated no other lesions, and the patient was diagnosed as having a solitary pulmonary MALT lymphoma (Stage IE). Establishment of a integrative multi-omics expression database CKDdb in the context of chronic kidney disease (CKD). Within the past few years, the invention of next-generation sequencing has revealed several new genes associated with tumor formation and development, for example DNMT3a. In comparison with the corresponding control, the placental Pgp protein significantly decreased on GD 15 and GD 18.

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Occasional cells within the suprabasal layers of the limbus stained positively for Ki67. Redox potential status in children with perinatal HIV-1 infection treated with zidovudine. The current status of computer-assisted instruction in the health sciences. Finally, we aim to provide perspectives to generate potential scientific evidence for the beneficial effects of nutraceuticals on human physiology. Based on the extension of cysticercosis, the study group was divided into patients with focal or diffuse cysticercal disease. A pseudoaneurysm of the pancreaticoduodenal artery secondary to altace medication chronic pancreatitis was erroneously diagnosed as a pancreatic pseudocyst by abdominal plain films, barium gastrointestinal studies, and abdominal ultrasound. In order to asses the extent of metabolic damage incurred by surgical preparation, adenosine triphosphate (ATP) levels were also measured. The primary function of the coagulation cascade is to promote haemostasis and limit blood loss in response to tissue injury. We demonstrate that without any conventional fine segmentation followed by explicit feature extraction, the proposed deep-learning algorithms effectively classify the coarsely localized cell lines.

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